Adant is a hyaluronic acid injection.

Hyaluronic acid, also known as sodium hyaluronate, is a substance found naturally in the body. Hyaluronic acid occurs naturally in joints and cartilage. Hyaluronic acid is the main component of synovial fluid and ensures the proper functioning of joints.

Hyaluronic acid can be applied in the treatment of complaints related to osteoarthritis.

Hyaluronic acid injection increases synovial fluid and improves its quality. Hyaluronic acid protects the cartilage of the joint.

It reduces pain and restores mobility in the short and long term.
Adant exists in two versions, Adant and Adant
A. Ask your doctor which variation is best to use in your situation.

Benefits

Significantly reduces joint swelling and pain.
Positive long-term results.
Clinical data (AMELIA study) show an improvement in the symptoms of knee osteoarthritis after 3.4 years of treatment, with one repetition of Adant per year.
Safe to use.
Adant is approved in more than 45 countries and has been used in more than 13 million treatments on patients worldwide.
Produced by biotechnology (bacterial fermentation).
The hyaluronic acid contained in Adant is not of animal origin. This reduces the risk of allergic reactions and makes it safe to use.

For up to 3 to 5 consecutive weeks, one injection of Adant per week into the affected joint will relieve your symptoms for approximately 6 to 9 months1.

Indications
Osteoarthritis of the knee and scapulohumeral periarthritis. Grades I, II and III of trapezoidal metacarpal osteoarthritis. Pain and reduced mobility due to degenerative and traumatic changes in other synovial joints.

Contraindications
The product is not recommended for patients with a history of hypersensitivity to the product.

Usage tips
In general, it is recommended to give one intra-articular injection per week for a maximum of 5 weeks. Administration should be into the intra-articular space of the knee joint, shoulder joint (intra-articular space of the shoulder joint, subacromial bursa or long tendon sheath of the biceps brachii), the trapeziometacarpal joint or the synovial joint concerned. In the latter case, two routes of administration are recommended depending on the degree of osteoarthritis: the external lateral route (grade I of rhizoarthrosis) and the interdigital/first commissure route (grades II and III of rhizoarthrosis). However, the choice of one or the other technique is made on a case-by-case basis; in this context, administration by endoscope is easier. In all cases, the dosage must be adapted according to the severity of the symptoms. Recent clinical data (AMELIA study) show the positive long-term effects of ADANT after 3.4 years of treatment: an improvement in the symptoms of osteoarthritis in the knee, with one ADANT cycle per year.

Precautions for use
This product may worsen local inflammation in patients with osteoarthritis of the knee who have an inflamed and swollen joint. It is therefore recommended to administer the product after the disappearance of the local symptom. In rare cases, local pain may appear after administration of the product. To avoid any post-injection pain, the patient should be asked to rest the local treatment site after the injection. The product must be injected precisely into the intra-articular space, otherwise pain may appear. ADANT should be administered with caution to patients with a history of hypersensitivity to other drugs and to patients with hepatic insufficiency or dysfunction. Administration to the elderly: The product should be administered with caution, as physiological functions are generally limited in these patients. Administration to Children: The product should be administered with caution to children as the safety of this product in children has not been established. Administration to pregnant or lactating women: Although no teratogenic effects have been observed in animals, the safety of this product for pregnant women has not been established. The product should therefore be administered with caution to women who are pregnant or suspected of being pregnant. Sodium hyaluronate is secreted in the milk of treated animals, therefore it is recommended to interrupt breastfeeding during treatment.

Side effects
In some patients, rare cases of skin rashes such as hives and pruritus may occur. In this case, treatment should be discontinued and the patient should receive appropriate treatment. Rarely,