For dogs affected or at risk of mixed parasitic infestations:
– prevention and treatment of infestations by fleas (Ctenocephalides felis).
– treatment of infestations by biting lice (Trichodectes canis).
– treatment of ear mites (Otodectes cynotis), sarcoptic mange (due to Sarcoptes scabiei var. canis), canine demodicosis (due to Demodex canis).
– prevention of heartworm disease (L3 and L4 larvae of Dirofilaria immitis).
– treatment of circulatory microfilariae (Dirofilaria immitis).
– treatment of cutaneous dirofilariosis (adult stage of Dirofilaria repens).
– prevention of subcutaneous dirofilariosis (L3 larvae of Dirofilaria repens).
– reduction of circulatory microfilariae (Dirofilaria repens).
– prevention of angiostrongylosis (L4 larva and immature adults of Angiostrongylus vasorum).
– treatment of angiostrongylosis (Angiostrongylus vasorum) and Crenosoma vulpis.
– prevention of spirocerciasis (Spirocerca lupi).

– treatment of nasal capillariasis in dogs caused by Eucoleus (syn. Capillaria) boehmi (adults).

– treatment of thelazia caused by Thelazia callipaeda (adults).
– treatment of infestations by gastrointestinal nematodes (L4 larvae, immature adults and adult forms of Toxocara canis, Ancylostoma caninum and Uncinaria stenocephala, and adult forms of Toxascaris leonina and Trichuris vulpis).

The drug can be integrated into a therapeutic program for flea bite allergic dermatitis (DAPP).